matthew
Member
- Location
- Cornwall, SW England
I'm quite happy to have a third jab but it will be with the Pfizer one or not at all.
If you now work within the NHS, you won't have a choice, will you?
No jab, no job?
I'm quite happy to have a third jab but it will be with the Pfizer one or not at all.
If you now work within the NHS, you won't have a choice, will you?
No jab, no job?
just read an article in the Telegraph saying AZ gives a far better long term T Cell responseI'm not currently doing any paid work but I suspect I will be obliged to have a booster at some stage or they could theoretically withhold all my clinical placements.
Having had 2 jabs already it would perverse to decline or refuse a third. I would prefer it to be Pfizer though.
just read an article in the Telegraph saying AZ gives a far better long term T Cell response
If the Pfizer vaccine is less durable, it might explain why countries with apparently similar levels of vaccination to the UK - but with Pfizer the predominant jab - are now experiencing higher levels of hospitalisation and deaths. The seemingly better T-cell response that comes from the AstraZeneca vaccine may mean it gives longer protection, despite an apparently inferior initial antibody response.
After having had the first 2 AZ (Vaxzevria) in February and April and had an blood antibody test which recorded no sign of antibodies I got my Pfizer booster in October and took another antibody test which came back reassuringly positive.I have no doubt the AZ vaccine does generate a strong T cell response.
But I have read articles talking about the longevity of the effect conferred by the Pfizer vaccine:
mRNA vaccines spur lymph nodes for longer-term protection; COVID-19 test accuracy may vary by time of day
The following is a roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus.www.reuters.com
(Reuters) - The following is a roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus.
mRNA vaccines spur lymph nodes for longer-term protection
Along with inducing antibodies for immediate defense, mRNA vaccines against COVID-19 also stimulate the lymph nodes to generate immune cells that provide protection over the long term, a new study confirms. The early wave of antibodies are generated by B cells called plasmablasts. In healthy volunteers, blood tests showed that two doses of the Pfizer/BioNTech vaccine induced "a strong plasmablast response," said coauthor Ali Ellebedy of Washington University School of Medicine in St. Louis. The immune cells that will produce antibodies upon exposure to the virus in years to come - called memory B cells - are generated by germinal center B cells found only in lymph nodes near vaccine injection sites, his team explained in a paper currently undergoing peer review for possible publication in a Nature journal. In repeated biopsies of volunteers' lymph nodes, "we saw a robust germinal center response," Ellebedy said. The responses lasted at least seven weeks, "with no sign of cooling down anytime soon," he added. "While we do not have long-term samples yet, it is safe to assume given the magnitude and persistence of the germinal center reaction that those individuals will develop a durable immune response" to mRNA vaccines. Moderna Inc's vaccine also uses mRNA technology. (bit.ly/3tnAiYw)
I suspect that you got the Pfizer Cominarty vaccine this time? Almost certainly not the AZ.I had 2 AZ earlier in year, off for booster today, hope its 2AZ again
You are correctI suspect that you got the Pfizer Cominarty vaccine this time? Almost certainly not the AZ.
Glad you're feeling better, @D14 , and hope you and the rest of your family stay well.
If this virus had anything to be cunning with, it would be much more cunning than a dodgy government. Our government has taken a hybrid approach to stopping our "share" of the pandemic, so it's bound to be a more jumbled process than groups of countries which took harder or softer actions.
Some good news: immunity from the wild virus is included in eligibility for a pass, although there are some exceptions ~Yes I can see that but we do seem to be worse off than many other countries. Ok we do have a higher population figure than some others but I still am not sure this is what it actually is. Having had it twice then I have the antibodies so why should I be classed as a person without a covid passport.
Now it actually does not bother me presently because I wouldn't normally attend any events such as a concert or sports fixture and I have to say I am not bothered about travelling abroad presently. However I would be bothered if in January i can't go into a pub or restaurant for example or can't go to a theme park or zoo with the children. And what I will not tolerate is my children having to have the vaccine as for me its not an option in any way at all at the ages of 12 and 8. I kept my eldest off school the day the did the vaccines because they school were really pushing the children to have it via Gillick Competance. I have since learned that on that day out of 900 children in the school there was 440 off school. Of the remainder in school I have no idea if they did or did not have the vaccine but I think the talking to fellow parents I would go as far as saying maybe only 20% had it.
Some good news: immunity from the wild virus is included in eligibility for a pass ~
Covid passports | Institute for Government
Covid passports are a way of proving that a person has been vaccinated against (or in some cases recovered from or tested negative for) Covid-19.www.instituteforgovernment.org.uk
With vaccination of children, it's the decision of their parent or guardian. It isn't compulsory.
I know its not compulsory and we did not agree to it. But the school then took it upon themselves to start talking about it regularly trying to convince the pupils that it was the 'right and responsible' thing to do. We then had a letter detailing Gillick Competence which basically said your child can decide to have it even if you have not agreed. The school talking about it went on for weeks and it was even being dropped into lessons. Totally inappropriate and I along with numerous parents complained to the head of year and also the head teacher and we have never had any form of response. It just looks and feels underhand.
That's a tricky one, isn't it. The school does have a duty to make sure that pupils are informed of options, and might be standing up to misinformation, or even disinformation circulating in its catchment.