How do you inject sheep with cydectin?

sherg

Member
Location
shropshire
got a feeling when they tested the product they did all the trials jabbing under the ear so that's why its licensed for use there but its fine under the skin in the neck
 

bovine

Member
Location
North
got a feeling when they tested the product they did all the trials jabbing under the ear so that's why its licensed for use there but its fine under the skin in the neck
Your 'feeling' doesn't go along with the published data sheet or what the drug company have told me. You're a brave man using it anywhere else.

1% Cydectin says 'inject in the neck'. This is very specific, presumably for a reason.
 

bovine

Member
Location
North
Well they should me more specific to the reasons why. Used it first time this year did first batch in ear on Swales took forever.
The data sheet that comes with product isn't in there for fun. It's not for some bedtime reading if struggling to sleep. It states quite clearly:

CYDECTIN 20 mg/ml LA for Sheep has been formulated specifically for subcutaneous injection in the base of the ear of sheep and must not be given by any other route of administration or to any other species.

They don't need to tell you why - follow the instructions!
 
Our vets are very hot on promoting drench resistant testing, FEC and use of Zolvix/Startect once a year, but they also appear to be persuading everyone locally to use Cydectin LA as a lambing dose for cleaning pasture. Maybe there's a good margin to be had in Zolvix sales?;)
We've only started using Cydectin on lambs for the past 2 years but am worried that if I do the ewes at lambing time I will increase the chance of resistance. I've heard others say how good Cydectin is if given to ewes but not sure myself. We'd need to give a white wormer to lambs for nematodirius as we have nemo present on the farm so not sure of the value of the "hoovering" benefit of Cydectin. What do you think @neilo about a pre/post lambing dose of Cydectin for ewes?
 

neilo

Member
Mixed Farmer
Location
Montgomeryshire
Please avoid Cydectin if you possibly can. You push so hard for resistance it is not sustainable - long term.

I used it for the first time this year, and I know that a hell of a lot of others locally are too. Because I jabbed with Cydectin LA, instead of using Cydectin drench, I wormed my lambs once with white drench for nemo in mid-late May, then again at weaning. The retained ewe lambs have been drenched (again with Ivermectin) to treat suspected lungworm this Autumn, and are back rotationally grazing the same PP the ewes & lambs were on. As mentioned above, that group are to be used for a drench resistance study by HCC, and they need to be at 500 epg before we can start that. We are testing them regularly, but they are still only sitting at 250-300. Something cleared something up, and I've certainly used a lot less clear drench as a result.

Is this better or worse for drench resistance? And yes, I get the point about the ai tailing off and sub-lethal doses. The figures for %age of farms with resistanec to white & yellow drench is pretty scary, and I suspect the vast majority would be using an ineffective treatment by rotating wormers now. That horse may well have bolted.(n)
 

bovine

Member
Location
North
Different years are better than others for worms. It's quite possible that this was a good year - so you'd need less wormer by chance. The Cydectin would no doubt reduce worms on pasture (how close to lambing were you drenching before?). We have some farms who only worm lambs twice in the season and don't need Cydectin. The worrying thing is if we have sheep full of Cydectin, all the worms they consume will be exposed. Slowly all the susceptible worms will die and whilst total burden reduces the resistant population increases. Continue with the selection pressure and this process is accelerated.

The problems we have with wormers now were caused in the main by short acting products. Imagine using a white or yellow drench (or simple ivermectin). The product is active for maybe a day and then gone - maybe one a month for 8 months of the year. It took years for significant resistance to emerge. Throw in a product that is there for 100 days plus and you are exposing the worm population to the equivalent of over 12 years exposure of a short acting product (based on 100/8).

One critical factor in minimising resistance is the concept of refugia - the part of the worm population not exposed to a product. This is why brought in animals should be turned out to dirty pasture - any odd remaining resistant worms are massively diluted. If you recycle these worms through sheep containing a long acting product you have problems.

From the Cydectin 2% data sheet you will see the product is active against haemonchus for 111 days, but only 44 days against trichostrongylus. Clearly some parasites are being exposed for as much as 2 months at sub lethal doses.

If you are trying to reduce overall total burden you can use one of the new products (Zolvix or Startect) mid summer when the weather is dry and the majority of worms are in the sheep. They don't exert a prolonged selection pressure and there is no known resistance (which there is to the group 3 - Cydectin family).

This is one of those cases where the product works as it should, but its use in this way is not sustainable in the long term. Have I explained why?
 

GTB

Never Forgotten
Honorary Member
We and most other farmers around here use Cydectin injection as a tool to control scab. The worming aspect is very handy but definitely secondary to scab control.

We inject all our breeding stock in the autumn and sometimes again pre-housing/lambing if they have been in contact with scab infested sheep. We then dose the lambs with white drench in mid may and again with a different product at weaning. Perhaps we should use Zolvix at weaning?
 

bovine

Member
Location
North
Showers not good enough for scab (must be plunge dip).

@GTB I would strongly consider Zolvix at weaning.

It doesn't matter what you are using the Cydectin for, the effect is the same. If using it at housing for scab prevention then there is much less risk as the animals not reinfecting with worms out at pasture.
 

neilo

Member
Mixed Farmer
Location
Montgomeryshire
This is one of those cases where the product works as it should, but its use in this way is not sustainable in the long term. Have I explained why?

If that's aimed at me, then I already knew why.;) It's the first time I've used it and it does appear to have done the trick of hoovering the pasture clean(er). I understand that there are one hell of a lot of people using it as a lambing dose around here, on advice from several different vet practices, and for running hogs.
 

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