Sheep unexpected deaths

Teddy6677

New Member
Hi, a friend of mine is having a problem with his sheep. He bought ew lambs last October didn't turn a ram to them. But 2 died and 1 went very sick with exactly the same symptoms. They were laying on their back kicking their legs unable to move. The vet told him it was vitamin b12 defishancy and she got better after the vitamin injection but now she is blind!!! Has anyone got any experience or got any advice on the matter?? Could it be a defishancy in the field their grazing or a polluted water source?? Many thanks
 

yellowbelly

Member
Livestock Farmer
Location
N.Lincs
Sounds like CCN. Probably triggered by a movement to a new environment.
Have a read of this....
Polioencephalomalacia (Cerebrocortical necrosis CCN).
History

Polioencephalomalacia (PEM) is most commonly seen in weaned lambs aged 4 to 8 months but disease does occur in adult sheep. Individual lambs are usually affected approximately two weeks after movement to another pasture or other dietary change. During the early stages of PEM affected sheep are blind and become isolated from the group and may wander aimlessly. There is 'star-gazing' when stationary. The condition deteriorates within 12 to 24 hours to lateral recumbency with seizure activity during handling. Without treatment, death follows within 3 to 5 days in untreated sheep.

053111_1248_NervousDise12.png


Fig 11: During the early stages of PEM affected sheep are blind and become isolated from the group.
053111_1248_NervousDise13.png


Fig 12: During the early stages of PEM affected sheep are blind and become isolated from the group.
053111_1248_NervousDise14.png


Fig 13: There is 'star-gazing' when stationary.


053111_1248_NervousDise15.png


Fig 14: The condition deteriorates within 12 to 24 hours to lateral recumbency with seizure activity
History


  • weaned lambs aged 4 to 8 months but occasionally adult sheep
  • pasture or other dietary change
Clinical signs

  • blind
  • become isolated
  • wander aimlessly
  • 'star-gazing'
  • recumbency with seizure activity
Diagnosis

Diagnosis is based upon veterinary examination.

Treatment

The treatment response during the early clinical stages of PEM to high doses of thiamine, (10 mg/kg bid) administered intravenously for the first occasion, is generally good. Successfully treated sheep are able to stand and commence eating within 24 hours although normal vision may not return for 5 to 7 days. Treatment should be continued for three consecutive days.

  • Intravenous thiamine (vitamin B1)
  • Three consecutive days' treatment
053111_1248_NervousDise16.png


Fig 15: The treatment response during the early clinical stages of PEM is generally good (see below).
053111_1248_NervousDise17.png


Fig 16: The same sheep as above after treatment.
 

bovine

Member
Location
North
B1 (CCN) much more likely than B12 deficiency (pine).

Would always advise PM's of dead animals. Histopathology of the brain will confirm the diagnosis of CCN.
 

Old Boar

Member
Location
West Wales
Thanks to this forum, a sheep I had with thiamin deficiency (vet confirmed) was saved by continuing the multi vit drench for about 2 weeks longer than the vet advised. She was blind and I was about to give up but she came good and it is difficult to see the difference between her and her sisters, apart from the fact she is friendly.
 

bovine

Member
Location
North
the multi vit drench

The affected sheep produce an enzyme (thiaminase) in the rumen that breaks down the thiamine. Drenches do not help the condition. If it got better with oral therapy then it was despite treatment, rather than as a result of it! Animals have an intrinsic ability to get better, this is why people think homoeopathy works.

As has been linked, treatment is by injection of B1 (ideally IV in the first instance).
 

Agrivator

Member
In an emergency, drench with a couple of desert spoons of Marmite dissolved in warm water.

But use a clean spoon, don't dribble down the jar, and replace in the kitchen cupboard to avoid arousing suspicion.

Marmite contains a whole range of B Vitamins.
 

Old Boar

Member
Location
West Wales
The affected sheep produce an enzyme (thiaminase) in the rumen that breaks down the thiamine. Drenches do not help the condition. If it got better with oral therapy then it was despite treatment, rather than as a result of it! Animals have an intrinsic ability to get better, this is why people think homoeopathy works.

As has been linked, treatment is by injection of B1 (ideally IV in the first instance).

I shall ask for my money back...
 

Paul E

Member
Location
Boggy.
In an emergency, drench with a couple of desert spoons of Marmite dissolved in warm water.

But use a clean spoon, don't dribble down the jar, and replace in the kitchen cupboard to avoid arousing suspicion.

Marmite contains a whole range of B Vitamins.


Sounds a faff to me.
Just stick the entire jar, suppository style:facepalm::stop: -
but remember to take the lid off first!!:confused:

Or you could try giving it to the ewe.
If it is CCN you've to hit it hard and early.
 

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