primmiemoo
Member
- Location
- Devon
Ah, but you'd get the hoity-toitys screaming blue murder about taking liberties.
They would never volunteer, either. Far too self-important.
The "I`ve got it" thread...
- Thread starter JCMaloney
- Start date
Ah, but you'd get the hoity-toitys screaming blue murder about taking liberties.
They would never volunteer, either. Far too self-important.
RushesToo
Member
- Location
- Fingringhoe
There is a form of pooled testing being undertaken, visual example below:I have to wonder why the Government (useless) has not introduced bulk sample testing if they are so short of capacity as claimed. We have done this in livestock testing for decades and it could reduce( or increase) the amount of tests required by a minimum of 50% and probably nearer 70 to 80% with no real reduction in accuracy. One can only assume that as the snouts in the trough brigade who run it are paid per sample they are against it.
And link to it here:
- Location
- Limousin
A ten sample is common in veterinary testing, but I've noticed that some African countries are using a 25 pooled sample I assume due to the shortage of capacity. However, a number of US trials see 8 as being the optimum number.
Forgot to say I was just talking about the traditional method of pooling. What they are showing is a more sophisticated method where an algorithm does the analysis and can id the positive sample. So there is then no need to resample a positive batch to find the individual one.
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- Location
- Scottish Highlands
Current positive test rate is running at around 6% in Scotland. I can see a lot more false positives being returned with a pooled regime. My own random trial suggested 6% genuine positive could give 7 false positive on a 10x10 grid.
- Location
- Scottish Highlands
I could see how it would work well when the number of positive sames is a very small percentage of the total. With what we have now, that is not the case and such a system would fall over very quickly.
Local numbers for local people.....
10,872 people in Leicestershire have tested positive - up from 10,808 (increase 64).
6558 (increase of 45) are within the Leicester City Council area.
4314 (increase of 19) cases in the County.
No change in deaths.
30 or so inpatients.
10,872 people in Leicestershire have tested positive - up from 10,808 (increase 64).
6558 (increase of 45) are within the Leicester City Council area.
4314 (increase of 19) cases in the County.
No change in deaths.
30 or so inpatients.
- Location
- Westish Suffolk
the conspiracy theorist in me thinks the latest Covid ramp up is more about deflecting the media away from Brexit issues that were starting to be the lead item in the news...
- Location
- Scottish Highlands
Can't really believe that Boris would get any cooperation from Nicola on that one.
One word ..... schools . might be wrong , but ...
- Location
- Limousin
You don't really get false positives on a PCR test. If there is it's usually down to some sort of contamination. False negatives are a different matter.
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- Location
- Scottish Highlands
I meant re the matrix testing method. If you try sticking half a dozen dots on the pooled test method above, then the number of rows and columns with a positive will add in some false positives. Get a grid on a sheet of paper and have a try. I got seven extra from six deliberate.
If anyone wants to know about matrix testing methodology and wants some bedtime reading... https://www.nature.com/articles/d41586-020-02053-6
And for PCR testing....
www.cebm.net
And for PCR testing....
Are you infectious if you have a positive PCR test result for COVID-19? - The Centre for Evidence-Based Medicine
Tom Jefferson, Carl Heneghan, Elizabeth Spencer, Jon Brassey PCR detection of viruses is helpful so long as its accuracy can
www.cebm.net
- Location
- Limousin
There is good explanation of algorithmic pooling here (5mins in) which also covers the false positives and negatives though the dilution of the samples.
BBC Radio 4 - More or Less: Behind the Stats, The magical maths of pool testing
Could pool testing hold the key to ramping up Covid-19 testing?
- Location
- Northern Ireland
But with respect, the number of infections isn't directly a problem. Of course it gives rise to illness, and there's a time lag. But illness is the only directly relevant measure surely?
- Location
- Scottish Highlands
That depends if you want to be proactive or reactive. For management of anything like this, you want to be using leading indicators rather than lagging ones.
The problem we have is with a very small minority .
Last week it has become appparent the Bolton outbreak was started by one geezer who didn't quarantine on return from Spain , went out on the razz with his mates and infected half the town
Should be locked up the tosser
Last week it has become appparent the Bolton outbreak was started by one geezer who didn't quarantine on return from Spain , went out on the razz with his mates and infected half the town
Should be locked up the tosser
Shot. He has helped ruin it for thousands of others. He is far from being alone unfortunately.