Is there anything visible that can be seen on PM, that would lead you to suspect Johne's in sheep? Or is it a lab sample job? I'll often do a PM myself, if the ewe is thin, mostly to check for fluke.
They have thickened corrugated hind guts. It seems to take on a yellow tinge. I have some preserved in formalin - I will try and get you a picture.
I would never make the diagnosis for the first time based on apparent gut thickening but it would be enough for me to be highly suspicious of the condition and send samples away. Once we knew we had the infection on a farm then I'd be happy using it to confirm that sheep's cause of death. It's quite subtle.
It should perhaps be mentioned that sheep do 'sometimes' just go downhill and die, without MV, Johnes or anything else being involved.
I'd generally disagree on that point. I'd say it was very rare indeed for us to PM a dead or very thin sheep and find nothing. Some of the finer points you develop having done 100's of sheep post mortems. I'm sure you guys can open up a sheep and see fluke or a massive lung tumour. Whether you notice the slightly soft kidneys and test its urine for glucose (pulpy kidney) or notice the gut is thickened are much less likely. We have farmers who do some PMs themselves and they tend to look at liver and lungs and not much else.
An old vet pathologist once told me that all sheep die of something. I tend to heed that advice. It's just whether you bother to look for it.......