Combining TB and MRSA - a "prevention" for TB?

[RushesToo]

@matthew Could you sanity check this for me. Someone has been funded to combine TB [very good at hiding itself from immune responses] with MRSA [not terribly responsive to drugs] to wake up the immune system and fight back. This surely has to be a level 4 biosecurity hazard. and generally a seriously bad idea?
http://www.bbc.co.uk/programmes/b07jqqv6 at 9:20
I think there is something I don't know, please can you explain?

 

[RushesToo]

I remember the failure in the neutralised polio vaccine and this sounds awfully similar.

 

[matthew]

My immediate reaction is that it was April 1st.

Both MRSA (Methicillin-resistant Staphylococcus aureus.) and m.bovis (Extensively drug resistant TB (XDR TB) or the multi drug resistant type (MDR TB) ) already have drug resistance, so combining the two in a GM cocktail...

This is work for a cattle vaccine, but other countries which have a known wildlife reservoir of m.bovis up spilling into other mammals, do something about it. Thus no need for a £0.24m spend at all.

I've asked some questions.

 

[RushesToo]

My immediate reaction is that it was April 1st.

Both MRSA (Methicillin-resistant Staphylococcus aureus.) and m.bovis (Extensively drug resistant TB (XDR TB) or the multi drug resistant type (MDR TB) ) already have drug resistance, so combining the two in a GM cocktail...

This is work for a cattle vaccine, but other countries which have a known wildlife reservoir of m.bovis up spilling into other mammals, do something about it. Thus no need for a £0.24m spend at all.

I've asked some questions.

Thank you.

 

[matthew]

Found this one from 2009.

http://www.ncbi.nlm.nih.gov/pubmed/19487476

Priming a vaccine is not new, but priming it with another pathogen?
Think this could be the culprit:

http://www.bath.ac.uk/bio-sci/contacts/academics/jean_van_den_elsen/

I have a pdf from Germany, describing the process, but can't copy/paste it.