The "I`ve got it" thread...

robs1

Member
after 4 weeks of lock down?:scratchhead:
If family member a has it on day one he/she becomes contagious in five to 14 days during this time family member b catches it and develops symptoms or not by their day 5 to 14 = 4 weeks by the time they present to hospital after a week or so, from all I have seen and read it comes in stages and it can take quite a while before it really hits your lungs, look at how long after Boris was a confirmed case before he was taken to hospital
 

RushesToo

Member
Location
Fingringhoe
Missus tells me the tests are hit and miss... They've tested some people 4 times with different results.

One with symptoms was negative another with no symptons tested as positive.

She applied online last night for home test kits for her. Be interesting to see.
I am sorry that this is very geeky, but it has some good background on why tests just need to be "good enough" and depending what you are asking "good enough" can actually be quite shite and still be useful.

TL: DR you need an OK test for people that are likely to be positive, but really good test to work across the whole population
 
Location
East Mids
Everyone thinks they may have it , but in fact few do .
Your interpretation of self isolation is different to mine .
but as they were not tested, no one (at present) can say they did not have it. There are plenty of reports of people being admitted to hospital NOT as covid cases, but then when tested, they had it. So I am not sure how you can pronounce who does and does not have it.
 

primmiemoo

Member
Location
Devon
There are two BBC Radio 4 programmes - Inside Health, and More or Less - that are consistent in addressing matters surrounding covid-19. They are available to listen to on BBC Sounds.

Most recently, they've looked at tests (or lack of accurate tests), testing (timings, etc), and infection rates of NHS and Care staff.

Highly recommended, because they are extremely thoughtful in their explanations.
 

Hindsight

Member
Location
Lincolnshire
Hence why the govt website today got overwhelmed in no time Was anybody else not surprised? :rolleyes:

I'm expecting those first tests to be fairly worthless with something like a 95% negative rate based on people wanting to be tested, rather than needing to be.

I wonder how many of those applying for tests were actually showing symptoms.

I disagree slightly. You may well be correct that people want to be tested rather than needed. But negative results are very helpful to understand the progress of the epidemic, albeit a self selecting group. Knowing how far and many folk have been infected is important to allow government to project the future path.
 

Hindsight

Member
Location
Lincolnshire
There are two BBC Radio 4 programmes - Inside Health, and More or Less - that are consistent in addressing matters surrounding covid-19. They are available to listen to on BBC Sounds.

Most recently, they've looked at tests (or lack of accurate tests), testing (timings, etc), and infection rates of NHS and Care staff.

Highly recommended, because they are extremely thoughtful in their explanations.

Well directed Sir. I am an avid follower of Tim Hartford.
 

Steevo

Member
Location
Gloucestershire
As an update to my earlier graphs on deaths by date of actual death, rather than the day the death was recorded....here is the latest info:

4D08A876-0D1A-46DD-BE7D-D5121FB3AA06.png

Looks more encouraging than the latest daily graph shown at the daily press briefing.
 
If that’s the case....how does washing your hands with soap for 20secs help?

I presume it is to remove any droplets of moisture or similar (maybe a biofilm) from your hands that might contain the virus rather than 'killing it' although detergents tend to grab hold of fats and other materials which is going to attract them to virus particles.

Details from:


And


The viruses we studied appeared to be somewhat more resistant to removal by washing with water and detergent. These differences could be due not only to the virus type but also to differences in the methods and laundering products used. Washing in warm or hot water does result in a greater reduction of virus (25). It is estimated that only 5% of all home laundering in the United States currently is done with hot water (E. Shaheen, Clorox Company, personal communication).

In conclusion, significant numbers of enteric viruses were found to survive washing and drying under conditions commonly practiced in households. Addition of sodium hypochlorite with detergent significantly reduced the numbers of viruses. Treatment with bleach alone reliably caused reductions of greater than 99.99%.


Enteric- pathogen that spreads faecal-orally basically. So I thought to myself, is Covid-19 one of those? It appears so:


Data exist to support the notion that SARS-CoV and MERS-CoV are viable in environmental conditions that could facilitate faecal–oral transmission. SARS-CoV RNA was found in the sewage water of two hospitals in Beijing treating patients with SARS. When SARS-CoV was seeded into sewage water obtained from the hospitals in a separate experiment, the virus was found to remain infectious for 14 days at 4°C, but for only 2 days at 20°C. SARS-CoV can survive for up to 2 weeks after drying, remaining viable for up to 5 days at temperatures of 22–25°C and 40–50% relative humidity, with a gradual decline in virus infectivity thereafter. Viability of the SARS-CoV virus decreased after 24 h at 38°C and 80–90% relative humidity. MERS-CoV is viable in low temperature, low humidity conditions. The virus was viable on different surfaces for 48 h at 20°C and 40% relative humidity, although viability decreased to 8 h at 30°C and 80% relative humidity conditions. At present, no viability data are available for SARS-CoV-2. The viability of SARS-CoV and MERS-CoV under various conditions and their prolonged presence in the environment suggest the potential for coronaviruses to be transmitted via contact or fomites. SARS-CoV and MERS-CoV are both viable in conditions with low temperatures and humidity. Although direct droplet transmission is an important route of transmission, faecal excretion, environmental contamination, and fomites might contribute to viral transmission. Considering the evidence of faecal excretion for both SARS-CoV and MERS-CoV, and their ability to remain viable in conditions that could facilitate faecal–oral transmission, it is possible that SARS-CoV-2 could also be transmitted via this route.

An also worth knowing:

In early reports from Wuhan, 2–10% of patients with COVID-19 had gastrointestinal symptoms such as diarrhoea, abdominal pain, and vomiting. Abdominal pain was reported more frequently in patients admitted to the intensive care unit than in individuals who did not require intensive care unit care, and 10% of patients presented with diarrhoea and nausea 1–2 days before the development of fever and respiratory symptoms.
SARS-CoV-2 RNA has been detected in the stool of a patient in the USA. The binding affinity of ACE2 receptors is one of the most important determinants of infectivity, and structural analyses predict that SARS-CoV-2 not only uses ACE2 as its host receptor, but uses human ACE2 more efficiently than the 2003 strain of SARS-CoV (although less efficiently than the 2002 strain).
 
I presume it is to remove any droplets of moisture or similar (maybe a biofilm) from your hands that might contain the virus rather than 'killing it' although detergents tend to grab hold of fats and other materials which is going to attract them to virus particles.

Details from:


And


The viruses we studied appeared to be somewhat more resistant to removal by washing with water and detergent. These differences could be due not only to the virus type but also to differences in the methods and laundering products used. Washing in warm or hot water does result in a greater reduction of virus (25). It is estimated that only 5% of all home laundering in the United States currently is done with hot water (E. Shaheen, Clorox Company, personal communication).

In conclusion, significant numbers of enteric viruses were found to survive washing and drying under conditions commonly practiced in households. Addition of sodium hypochlorite with detergent significantly reduced the numbers of viruses. Treatment with bleach alone reliably caused reductions of greater than 99.99%.


Enteric- pathogen that spreads faecal-orally basically. So I thought to myself, is Covid-19 one of those? It appears so:


Data exist to support the notion that SARS-CoV and MERS-CoV are viable in environmental conditions that could facilitate faecal–oral transmission. SARS-CoV RNA was found in the sewage water of two hospitals in Beijing treating patients with SARS. When SARS-CoV was seeded into sewage water obtained from the hospitals in a separate experiment, the virus was found to remain infectious for 14 days at 4°C, but for only 2 days at 20°C. SARS-CoV can survive for up to 2 weeks after drying, remaining viable for up to 5 days at temperatures of 22–25°C and 40–50% relative humidity, with a gradual decline in virus infectivity thereafter. Viability of the SARS-CoV virus decreased after 24 h at 38°C and 80–90% relative humidity. MERS-CoV is viable in low temperature, low humidity conditions. The virus was viable on different surfaces for 48 h at 20°C and 40% relative humidity, although viability decreased to 8 h at 30°C and 80% relative humidity conditions. At present, no viability data are available for SARS-CoV-2. The viability of SARS-CoV and MERS-CoV under various conditions and their prolonged presence in the environment suggest the potential for coronaviruses to be transmitted via contact or fomites. SARS-CoV and MERS-CoV are both viable in conditions with low temperatures and humidity. Although direct droplet transmission is an important route of transmission, faecal excretion, environmental contamination, and fomites might contribute to viral transmission. Considering the evidence of faecal excretion for both SARS-CoV and MERS-CoV, and their ability to remain viable in conditions that could facilitate faecal–oral transmission, it is possible that SARS-CoV-2 could also be transmitted via this route.

An also worth knowing:

In early reports from Wuhan, 2–10% of patients with COVID-19 had gastrointestinal symptoms such as diarrhoea, abdominal pain, and vomiting. Abdominal pain was reported more frequently in patients admitted to the intensive care unit than in individuals who did not require intensive care unit care, and 10% of patients presented with diarrhoea and nausea 1–2 days before the development of fever and respiratory symptoms.
SARS-CoV-2 RNA has been detected in the stool of a patient in the USA. The binding affinity of ACE2 receptors is one of the most important determinants of infectivity, and structural analyses predict that SARS-CoV-2 not only uses ACE2 as its host receptor, but uses human ACE2 more efficiently than the 2003 strain of SARS-CoV (although less efficiently than the 2002 strain).
I am reliably informed by a friend who works in cancer research that some poor sods are researching the potential of cv19 spread via farts.

Letting a silent one off next to someone in the supermarket and scuttling away so they get the blame could turn out to be much more anti-social than previously thought. Maybe shorts and short skirts will have to be banned in public places.

:unsure:
 

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