Has Covid lived up to your expectations?

___\0/___

Member
Location
SW Scotland
One of my wife's work colleagues was ill for most of last year and put it down to covid turns out she had cancer and has about a month to live. I haven't been great either so got marched of to the docs tests came back clear but I am showing signs similar to those with long covid.

Went from knowing a handful of people with it to lots just starting before Christmas majority have bounce back to normal very quickly.
 

Sonoftheheir

Member
Arable Farmer
Location
West Suffolk
As an aside, there are lot more people about on the roads today, ploughing near an A road it’s quite busy for an early Saturday morning.

Also I note that people in their 50’s are getting the jab around here now.
 

RushesToo

Member
Location
Fingringhoe
The virus is having a serious effect on all aspects of society, the damage at the moment should be considered at the lessor end of a scale.
High numbers of infectious people give the virus a chance to mutate. Currently it is only killing older people, so stopping it spreading before a variant starts attacking youngsters is a really important aim.

This isn’t just flu:
at the moment it is hitting older people and even the most charitable me feels this is a better option than youngsters dying.

What is absolutely essential is that chances of mutation is stopped by behaviour until vaccines can do the job before a mutant evolves that kills youngsters.
 

RushesToo

Member
Location
Fingringhoe
The virus is having a serious effect on all aspects of society, the damage at the moment should be considered at the lessor end of a scale.
High numbers of infectious people give the virus a chance to mutate. Currently it is only killing older people, so stopping it spreading before a variant starts attacking youngsters is a really important aim.

This isn’t just flu:
at the moment it is hitting older people and even the most charitable me feels this is a better option than youngsters dying.

What is absolutely essential is that chances of mutation is stopped by behaviour until vaccines can do the job before a mutant evolves that kills youngsters.
To explain, if a dangerous mutant comes out every 1 in a million infections, less than a million is a good target. Fortunately this is a slower mutating virus - bt we won't keep getting lucky.
 

essex man

Member
Location
colchester
To explain, if a dangerous mutant comes out every 1 in a million infections, less than a million is a good target. Fortunately this is a slower mutating virus - bt we won't keep getting lucky.
It's not about luck, successful mutations spread more easily by residing higher in respiratory tract, rendering them less harmful to younger people.
 

Guleesh

Member
Livestock Farmer
Location
Isle of Skye
The virus is having a serious effect on all aspects of society, the damage at the moment should be considered at the lessor end of a scale.
High numbers of infectious people give the virus a chance to mutate. Currently it is only killing older people, so stopping it spreading before a variant starts attacking youngsters is a really important aim.

This isn’t just flu:
at the moment it is hitting older people and even the most charitable me feels this is a better option than youngsters dying.

What is absolutely essential is that chances of mutation is stopped by behaviour until vaccines can do the job before a mutant evolves that kills youngsters.

The virus isn't flu but a strain of what we call the common cold. Its worth looking at the 1918 spanish flu epidemic which has been studied in great detail, widely regarded as the most deadly pandemic.

The worst affected age group centred around 28 yr olds, The reason they died is because of there inability to produce the correct antibody. The reason they couldn't is because when that age group were infants they were subjected to what is known as russian flu. There is a process known as Original antigenic sin, Which effectively means the first exposure to a virus can 'fix' the immune system response to favour producing the same antibody as for the first virus exposed to for future virus with similar genomes. Those young adults that got russian flu fell into that category and died very quickly other deaths included the very old and some very young.

Spanish flu pandemic deaths ceased within 3 years.

It's fascinating stuff if you can be bothered to go through it all and for me raises some questions as to humanities current attempts to beat c19.

The potential vaccination of children, and potential of lower then usual rates of common cold are also things that concern me.
 

RushesToo

Member
Location
Fingringhoe
It's not about luck, successful mutations spread more easily by residing higher in respiratory tract, rendering them less harmful to younger people.
Mutations are random, one may become more prominent by infecting the upper respiratory tract and spread better – so infectiousness becomes higher – and this is what the Kent variant does. Another could become more deadly but less “catchable” and target the young. Randomness can change many things.

MERS an earlier coronavirus had a case fatality rate of 10%. It was fortunately not terribly catchable.

Random can do this, it has no purpose it just happens.
 

oldoaktree

Member
Location
County Durham
I’ve not read any of this forum but for me it’s been a barrel of laughs. I caught Covid in October and felt ok , not great but didn’t think I was particularly unwell. Mrs kept checking my oxygen levels and wasn’t happy with them. She persuaded me me to go to Aand E it was touch and go weather I’d be kept in and put on oxygen. Thankfully I wasn’t. If my Mrs wasn’t a specialist respiratory nurse who could spot problems with my health then things could have been at lot worse for me. I’m pretty fit and Active probably a bit over weight but similar to every other one of my friends I’ve not seen for a year now.
 

RushesToo

Member
Location
Fingringhoe
Mutations are random, one may become more prominent by infecting the upper respiratory tract and spread better – so infectiousness becomes higher – and this is what the Kent variant does. Another could become more deadly but less “catchable” and target the young. Randomness can change many things.

MERS an earlier coronavirus had a case fatality rate of 10%. It was fortunately not terribly catchable.

Random can do this, it has no purpose it just happens.
@essex man it would be highly unlikely but not impossible that a mutation arose that was more fatal and affected younger people.
 

Guleesh

Member
Livestock Farmer
Location
Isle of Skye
Mutations are random, one may become more prominent by infecting the upper respiratory tract and spread better – so infectiousness becomes higher – and this is what the Kent variant does. Another could become more deadly but less “catchable” and target the young. Randomness can change many things.

MERS an earlier coronavirus had a case fatality rate of 10%. It was fortunately not terribly catchable.

Random can do this, it has no purpose it just happens.

Well, no it's not impossible, It's mutated several times already.

Still there's more to the human immune response system than meets the eye, and there's also other factors and other future risks that I think need consideration.

As you say random has no purpose, It's all unknown territory, we are subjected to our status of being mere hosts of a randomly mutating arms race between our cells and viruses that has been going on since day dot.

Just seems a bit silly to me to think we are above it as a species and can control it.
 

RushesToo

Member
Location
Fingringhoe
Well, no it's not impossible, It's mutated several times already.

Still there's more to the human immune response system than meets the eye, and there's also other factors and other future risks that I think need consideration.

As you say random has no purpose, It's all unknown territory, we are subjected to our status of being mere hosts of a randomly mutating arms race between our cells and viruses that has been going on since day dot.

Just seems a bit silly to me to think we are above it as a species and can control it.
The less of it we have around, the less chance it will mutate into something nasty. We should try and not win the Darwin award by letting it have enough chances to win.
 

Guleesh

Member
Livestock Farmer
Location
Isle of Skye
The less of it we have around, the less chance it will mutate into something nasty. We should try and not win the Darwin award by letting it have enough chances to win.

It can't win if it kills its hosts too quickly. Fast killing strains don't give themselves time to clone themselves and spread. It will always be held in some kind of balance, It's a symbiosis.
 

puppet

Member
Livestock Farmer
Location
sw scotland
Mutations are random, one may become more prominent by infecting the upper respiratory tract and spread better – so infectiousness becomes higher – and this is what the Kent variant does.
Do all mutations not infect the upper respiratory tract? Does the infectiousness not relate to how easily the virus enters your cells?
 

RushesToo

Member
Location
Fingringhoe
Do all mutations not infect the upper respiratory tract? Does the infectiousness not relate to how easily the virus enters your cells?
It's not totally known because no one wants to be guinea pigs and try it out. It is definitely airborne but may also be touch carried so don’t rub your eyes.
How eaily virus enters cells is important but so is how "hidden" it is from your immune system and whether it triggers an quick reaction from your immune system.

If you are interested there are some really good scientists telling it in understandable terms on twitter. If it isn't in your background it is hard to get upto speed quickly - it takes a lifetime to get how sheep want to die and how to stop them and the same for crops. Virology is much the same.
 

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